Flexibility of Human Cardiac α-Tropomyosin: Implications in Familial Hypertrophic Cardiomyopathy
α-Tropomyosin is the predominant tropomyosin isoform in adult human heart and constitutes a major component in Ca2+-regulated systolic contraction of cardiac muscle. Cardiac thin filaments are activated as Ca2+ induced conformational changes of the troponin complex lead to azimuthal movement of the...
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| Format: | Others |
| Language: | English English |
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Florida State University
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| Online Access: | http://purl.flvc.org/fsu/fd/FSU_migr_etd-5394 |