Disruption of Mitochondrial Dynamics in Tauopathy
Alzheimer’s disease (AD) is characterized pathologically by proteinaceous aggregates composed primarily of amyloid \(\beta (A \beta)\) and tau. Diseases characterized by abnormal deposition of tau are collectively termed “tauopathies.” \(A \beta\) acts upstream of tau in the AD pathogenesis path...
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Language: | en_US |
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Harvard University
2013
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Online Access: | http://dissertations.umi.com/gsas.harvard:10021 http://nrs.harvard.edu/urn-3:HUL.InstRepos:10276000 |