Regulation of the Fanconi Anemia Pathway by Deubiquitination

Regulation of the Fanconi Anemia Pathway by Deubiquitination

Fanconi anemia (FA) is a rare genetic disease characterized by bone marrow failure and cancer predisposition. Cell lines derived from FA patient exhibit chromosomal instability and sensitivity to DNA interstand crosslinkers (ICLs) like mitomycin (MMC). The key event in Fanconi anemia pathway is the...

Full description

Bibliographic Details
Main Author: Yang, Kailin
Other Authors: D’Andrea, Alan D.
Language:en_US
Published: Harvard University 2013
Subjects:
SUMO
biology
biochemistry
bioinformatics
deubiquitination
DNA repair
Fanconi anemia
ubiquitination
ubiquitin-binding domain
Online Access:http://dissertations.umi.com/gsas.harvard:10127
http://nrs.harvard.edu/urn-3:HUL.InstRepos:10288403

Internet

http://dissertations.umi.com/gsas.harvard:10127
http://nrs.harvard.edu/urn-3:HUL.InstRepos:10288403

Similar Items