Cytoprotective Pathways that Contribute to Lifespan Extension in C. elegans
Stress tolerance and lifespan are intimately associated. Extension of lifespan is accompanied by increased tolerance of heat, oxidative stress, radiation and other stressors, while genetic perturbations that abrogate lifespan extension compromise stress tolerance. The consistency of this correlation...
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| Language: | en_US |
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Harvard University
2013
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| Online Access: | http://dissertations.umi.com/gsas.harvard:10270 http://nrs.harvard.edu/urn-3:HUL.InstRepos:10288464 |