Re-Engineering the Tumor Microenvironment to Enhance Drug Delivery
Tumors are similar to organs, with unique physiology giving rise to an unusual set of transport barriers to drug delivery. Cancer therapy is limited by non-uniform drug delivery via blood vessels, inhomogeneous drug transport into tumor interstitium from the vascular compartment, and hindered transp...
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Language: | en_US |
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Harvard University
2013
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Online Access: | http://dissertations.umi.com/gsas.harvard:10405 http://nrs.harvard.edu/urn-3:HUL.InstRepos:10330313 |