Dissecting Protein-Protein Interactions that Regulate the Spindle Checkpoint in Budding Yeast
Errors in segregation of genetic materials are detrimental to all organisms. The budding yeast ensures accurate chromosome segregation by employing a system called the spindle checkpoint. The spindle checkpoint, which consists of proteins such as Mad1, Mad2, Mad3, Bub1, and Bub3, monitors the attach...
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| Language: | en_US |
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Harvard University
2013
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| Online Access: | http://dissertations.umi.com/gsas.harvard:10558 http://nrs.harvard.edu/urn-3:HUL.InstRepos:10364580 |