Estimating and Testing Treatment Effects and Covariate by Treatment Interaction Effects in Randomized Clinical Trials with All-or-Nothing Compliance

In this dissertation, we develop and evaluate methods for adjusting for treatment non-compliance in a randomized clinical trial with time-to-event outcome within the proportional hazards framework. Adopting the terminology in Cuzick et al. [2007], we assume the patient population consists of three (...

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Bibliographic Details
Main Author: Li, Shuli
Other Authors: Gray, Robert James
Language:en_US
Published: Harvard University 2013
Subjects:
Online Access:http://dissertations.umi.com/gsas.harvard:10554
http://nrs.harvard.edu/urn-3:HUL.InstRepos:10364611