Development and Application of a High-Throughput RNAi Screen to Reveal Novel Components of the DNA Sensing Pathway
The mammalian immune system has evolved a complex and diverse set of mechanisms to detect and respond to pathogens by recognizing conserved molecular structures and inducing protective immune responses. While many of these mechanisms are capable of sensing diverse molecular structures, a large fract...
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Language: | en_US |
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Harvard University
2013
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Online Access: | http://dissertations.umi.com/gsas.harvard:10918 http://nrs.harvard.edu/urn-3:HUL.InstRepos:11124826 |