Development and Application of a High-Throughput RNAi Screen to Reveal Novel Components of the DNA Sensing Pathway

The mammalian immune system has evolved a complex and diverse set of mechanisms to detect and respond to pathogens by recognizing conserved molecular structures and inducing protective immune responses. While many of these mechanisms are capable of sensing diverse molecular structures, a large fract...

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Bibliographic Details
Main Author: Roy, Matthew Stephen
Other Authors: Hacohen, Nir
Language:en_US
Published: Harvard University 2013
Subjects:
Online Access:http://dissertations.umi.com/gsas.harvard:10918
http://nrs.harvard.edu/urn-3:HUL.InstRepos:11124826