The function of the Heg-CCM pathway in zebrafish heart development
The Heart of glass-Cerebral Cavernous Malformation (Heg-CCM) pathway is essential for heart development in zebrafish and mouse. In zebrafish, mutants for the Heg-CCM genes ccm1, ccm2, and heg exhibit an extreme dilation of the heart chambers and inflow tract and completely lack blood circulation....
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| Language: | en_US |
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Harvard University
2013
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| Online Access: | http://dissertations.umi.com/gsas.harvard:10744 http://nrs.harvard.edu/urn-3:HUL.InstRepos:11151537 |