Induction of Mitotic Alterations by the Human Papillomavirus Type 16 E7 Oncoprotein: Mechanistic Studies

High-risk human papillomaviruses (HPVs) are causative agents of most cervical cancers and a significant portion of other anogenital tract and oral carcinomas. The major oncogenic activities of HPV16 E6 and E7 oncoproteins are associated with the degradation of the p53 and retinoblastoma tumor suppre...

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Bibliographic Details
Main Author: Yu, Yueyang
Other Authors: Munger, Karl
Language:en_US
Published: Harvard University 2013
Subjects:
Online Access:http://dissertations.umi.com/gsas.harvard:11112
http://nrs.harvard.edu/urn-3:HUL.InstRepos:11169778