Induction of Mitotic Alterations by the Human Papillomavirus Type 16 E7 Oncoprotein: Mechanistic Studies
High-risk human papillomaviruses (HPVs) are causative agents of most cervical cancers and a significant portion of other anogenital tract and oral carcinomas. The major oncogenic activities of HPV16 E6 and E7 oncoproteins are associated with the degradation of the p53 and retinoblastoma tumor suppre...
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Language: | en_US |
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Harvard University
2013
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Online Access: | http://dissertations.umi.com/gsas.harvard:11112 http://nrs.harvard.edu/urn-3:HUL.InstRepos:11169778 |