SIV envelope glycoprotein determinants of macrophage tropism and their relationship to neutralization sensitivity and CD4-independent cell-to-cell transmission

SIV envelope glycoprotein determinants of macrophage tropism and their relationship to neutralization sensitivity and CD4-independent cell-to-cell transmission

Macrophages are target cells for human immunodeficiency virus (HIV) and simian immunodeficiency virus (SIV) infection that serve as viral reservoirs in brain, lung, gut, and other tissues, and play important roles in disease pathogenesis, particularly HIV/SIV-associated neurological disease. Macroph...

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Bibliographic Details
Main Author: Yen, Po-Jen
Other Authors: Gabuzda, Dana Helga
Language:en_US
Published: Harvard University 2013
Subjects:
Virology
CD4-independence
Cell-to-cell transmission
HIV
Macrophage tropism
Neutralization sensitivity
SIV Envelope Glycoprotein
Online Access:http://dissertations.umi.com/gsas.harvard:11188
http://nrs.harvard.edu/urn-3:HUL.InstRepos:11169823

Internet

http://dissertations.umi.com/gsas.harvard:11188
http://nrs.harvard.edu/urn-3:HUL.InstRepos:11169823

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