The Role of Dendritic Cell Subsets in Cross-presentation and Stimulation of Homing Marker Expression
Topical antigen (Ag) application mimics natural Ag exposure across the skin. Soluble Ag introduced through this route requires cross-presentation by dendritic cells (DCs) to generate CD8 T cell responses, including skin-homing T cells. DCs process Ag for display to other immune cells, and stimulate...
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| Language: | en_US |
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Harvard University
2014
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| Online Access: | http://dissertations.umi.com/gsas.harvard:11224 http://nrs.harvard.edu/urn-3:HUL.InstRepos:11744415 |