Transcriptional and Epigenetic Dynamics Observed During Lineage Specification of Human Embryonic Stem Cells
Epigenetic regulation of gene expression is essential for faithful cellular specification during embryonic development. Directed differentiation of pluripotent human embryonic stem cells (hESCs), which maintain the ability to give rise to each cell type found within the human body, provides a tracta...
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| Language: | en_US |
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Harvard University
2014
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| Online Access: | http://dissertations.umi.com/gsas.harvard:11228 http://nrs.harvard.edu/urn-3:HUL.InstRepos:11744419 |