Identification and Characterization of Intermediates during Folding on the β-Barrel Assembly Machine in Escherichia coli
β-barrel membrane proteins play important structural and functional roles in Gram negative bacteria and in mitochondria and chloroplasts of eukaryotes. A conserved machine is responsible for the folding and insertion of β-barrel membrane proteins but its mechanism remains largely unknown. In E. coli...
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| Language: | en_US |
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Harvard University
2014
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| Online Access: | http://dissertations.umi.com/gsas.harvard:11594 http://nrs.harvard.edu/urn-3:HUL.InstRepos:12274188 |