Characterization and Optimization of the CRISPR/Cas System for Applications in Genome Engineering
The ability to precisely manipulate the genome in a targeted manner is fundamental to driving both basic science research and development of medical therapeutics. Until recently, this has been primarily achieved through coupling of a nuclease domain with customizable protein modules that recognize D...
| Main Author: | |
|---|---|
| Format: | Others |
| Language: | en |
| Published: |
Harvard University
2014
|
| Subjects: | |
| Online Access: | http://etds.lib.harvard.edu/hms/admin/view/61 http://nrs.harvard.edu/urn-3:HUL.InstRepos:12407619 |