The Role of Innate Immune IL-10 Receptor Signaling in Controlling Intestinal Immune Responses
Interleukin-10 (IL-10) is a key anti-inflammatory cytokine. Patients with deleterious mutations in either IL10 or its receptor (IL10R) develop severe inflammatory bowel disease (IBD) within the first months of life; similarly, Il10rb-/- mice develop spontaneous colitis. The precise mechanisms of IL-...
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| Format: | Others |
| Language: | en |
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Harvard University
2015
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| Online Access: | http://nrs.harvard.edu/urn-3:HUL.InstRepos:17613727 |