Targeting STAT3 in Ovarian Cancers: Reciprocal Activation of NF-kB by STAT3 Inhibition
The transcription factor STAT3 normally modulates cell proliferation with a rapid and transient downstream effect. However, in tumor cells, inappropriately activated STAT3 alters the gene expression profile and renders tumor cells unresponsive to cell death signals. In this study, we examine the bio...
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| Format: | Others |
| Language: | en |
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Harvard University
2016
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| Online Access: | http://nrs.harvard.edu/urn-3:HUL.InstRepos:27007758 |