Increased CKIP-1 suppresses Smad-dependent BMP signaling to inhibit bone formation during aging
Emerging evidence indicates that the dysregulation of protein ubiquitination plays a crucial role in aging-associated diseases. Smad-dependent canonical BMP signaling pathway is indispensable for osteoblastic bone formation, which could be disrupted by the ubiquitination and subsequent proteasomal d...
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| Format: | Others |
| Language: | English |
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HKBU Institutional Repository
2016
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| Online Access: | https://repository.hkbu.edu.hk/etd_oa/327 https://repository.hkbu.edu.hk/cgi/viewcontent.cgi?article=1327&context=etd_oa |