Conformational Regulation of the Essential Epigenetic Regulator UHRF1
UHRF1 is an essential epigenetic regulator implicated in the maintenance of DNA methylation. While its functional state has been suggested to be allosterically regulated by phosphatidylinositol 5-phosphate and dependent on purification conditions and tags coupled to the protein, the expression sy...
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| Language: | en |
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2018
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| Online Access: | http://hdl.handle.net/10754/627912 |