A single molecule view of FEN1 remarkable substrate recognition, perfect catalysis and regulation

A single molecule view of FEN1 remarkable substrate recognition, perfect catalysis and regulation

DNA replication is one of the most fundamental processes in all living organisms. Its semi-discontinuous nature dictates that the lagging strand is synthesized in short fragments called Okazaki fragments. In eukaryotes, each Okazaki fragment is initiated by an ~ 30-40 nucleotide-long RNA-DNA hybrid...

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Bibliographic Details
Main Author: Zaher, Manal
Other Authors: Hamdan, Samir
Language:en
Published: 2019
Subjects:
FEN1
FRET
Okazaki fragment maturation
single molecule
DNA replication
PIFE
Online Access:Zaher, M. (2019). A single molecule view of FEN1 remarkable substrate recognition, perfect catalysis and regulation. KAUST Research Repository. https://doi.org/10.25781/KAUST-UR19J
http://hdl.handle.net/10754/644895

Internet

Zaher, M. (2019). A single molecule view of FEN1 remarkable substrate recognition, perfect catalysis and regulation. KAUST Research Repository. https://doi.org/10.25781/KAUST-UR19J
http://hdl.handle.net/10754/644895

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