A single molecule view of FEN1 remarkable substrate recognition, perfect catalysis and regulation
DNA replication is one of the most fundamental processes in all living organisms. Its semi-discontinuous nature dictates that the lagging strand is synthesized in short fragments called Okazaki fragments. In eukaryotes, each Okazaki fragment is initiated by an ~ 30-40 nucleotide-long RNA-DNA hybrid...
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| Language: | en |
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2019
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| Online Access: | Zaher, M. (2019). A single molecule view of FEN1 remarkable substrate recognition, perfect catalysis and regulation. KAUST Research Repository. https://doi.org/10.25781/KAUST-UR19J http://hdl.handle.net/10754/644895 |