The medicinal chemistry of cyclo(D-Phe-2Cl-Pro) and cyclo(Phe-4F-Pro)
Although peptides and proteins are considered as lead compounds for the discovery and development of new therapeutic agents, poor metabolic and physical properties have limited their optimisation as drug candidates (Adessi & Soto, 2002). Research by medicinal chemists however, generated the disc...
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| Format: | Others |
| Language: | English |
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Nelson Mandela Metropolitan University
2011
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| Online Access: | http://hdl.handle.net/10948/7083 |