Development of a liposomal acyclovir mucoadhesive film

Acyclovir is a synthetic purine nucleoside analogue with in vitro and in vivo inhibitory activity against herpes simplex virus types 1 (HSV-1), 2 (HSV-2), and varicella-zoster virus (VZV). The efficacy of oral acyclovir is limited as a result of its low bioavailability (15-30%) as it is poorly water...

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Bibliographic Details
Main Author: Nalungwe, Sarah
Format: Others
Language:English
Published: Nelson Mandela Metropolitan University 2017
Subjects:
Online Access:http://hdl.handle.net/10948/14212