The synthesis and evaluation of phenoxymethylcaffeine analogues as inhibitors of monoamine oxidase / Braam Swanepoel
Purpose: Monoamine oxidase (MAO) plays a key role in the treatment of Parkinson‟s disease (PD), since it is the major enzyme responsible for the catabolism of dopamine in the substantia nigra of the brain. Inhibition of MAO-B may conserve dopamine in the brain and provide symptomatic relief. The MAO...
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Language: | en |
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North-West University
2013
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Online Access: | http://hdl.handle.net/10394/8428 |