The synthesis and evaluation of phenoxymethylcaffeine analogues as inhibitors of monoamine oxidase / Braam Swanepoel

The synthesis and evaluation of phenoxymethylcaffeine analogues as inhibitors of monoamine oxidase / Braam Swanepoel

Show other versions (1)

Purpose: Monoamine oxidase (MAO) plays a key role in the treatment of Parkinson‟s disease (PD), since it is the major enzyme responsible for the catabolism of dopamine in the substantia nigra of the brain. Inhibition of MAO-B may conserve dopamine in the brain and provide symptomatic relief. The MAO...

Full description

Bibliographic Details
Main Author: Swanepoel, Abraham Johannes
Language:en
Published: North-West University 2013
Subjects:
Parkinson‟s disease
Monoamine oxidase
Substantia nigra
8-benzyloxycaffeine
8-(phenoxymethyl)caffeine
Safinamide
(E)-8-(3-chlorostyryl)caffeine
Parkinsonisme
Monoamienoksidase
8-bensieloksiekafeïen
8-(fenoksiemetiel)kafeïen
Safienamied
(E)-8-(3-chlorosteriel)kafeïen
Online Access:http://hdl.handle.net/10394/8428

Internet

http://hdl.handle.net/10394/8428

Similar Items