Hsp90 co-chaperones as drug targets in cancer: current perspectives
publisher version === Hsp90 is a molecular chaperone that regulates the function of numerous oncogenic transcription factors and signalling intermediates in the cell. Inhibition of Hsp90 is sufficient to induce the proteosomal degradation of many of these proteins, and as such, the Hsp90 chaperone h...
Main Author: | |
---|---|
Format: | Others |
Language: | English |
Published: |
Springer International Publishing Switzerland
2016
|
Online Access: | http://hdl.handle.net/10962/66347 https://doi.org/10.1007/7355_2015_99 |