Structural analysis of effects of mutations on HIV-1 subtype C protease active site

HIV/AIDS is a global pandemic that poses a great threat especially in Sub-Saharan Africa where the highest population of those infected with the virus is found. It has far reaching medical, socio-economic and scientific implications. The HIV-1 protease enzyme is a prime therapeutic target that has b...

Full description

Bibliographic Details
Main Author: Mathu, Alexander Muchugia Nganga
Format: Others
Language:English
Published: Rhodes University 2012
Subjects:
Online Access:http://hdl.handle.net/10962/d1004073