The development of a baculovirus expression system for the production of Helicoverpa armigera stunt virus capsids for use in the encapsidation of foreign molecules

The capsid protein of Helicoverpa armigera stunt virus (HaSV) a T=4 insect virus was expressed in Spodoptera frugiperda 9 cells using a baculovirus vector. When the insect cells were infected at a high MOl the expressed coat protein assembled into virus-like particles (VLPs) that spontaneously under...

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Bibliographic Details
Main Author: Mosisili, Kekeletso Mpho Thakane
Format: Others
Language:English
Published: Rhodes University 2003
Subjects:
Online Access:http://hdl.handle.net/10962/d1007700