Studies towards the development of novel HIV-1 integrase inhibitors

Studies towards the development of novel HIV-1 integrase inhibitors

The project has focused on the preparation of several series of compounds designed as potential HIV-1 integrase inhibitors. Various 2-nitrobenzaldehydes have been reacted with two activated alkenes, methyl vinyl ketone (MVK) and methyl acrylate, under Baylis-Hillman conditions to afford α-methylene-...

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Bibliographic Details
Main Author: Lee, Yi-Chen
Format: Others
Language:English
Published: Rhodes University 2010
Subjects:
HIV infections > Treatment
HIV (Viruses)
AIDS (Disease) > Treatment
Nuclear magnetic resonance
Heterocyclic compounds > Derivatives
Enzyme inhibitors
Chemical inhibitors
Quinoline
Online Access:http://hdl.handle.net/10962/d1005022

Internet

http://hdl.handle.net/10962/d1005022

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