Synthesis of novel coumarin derivatives as potential inhibitors of HIV-1 protease

Synthesis of novel coumarin derivatives as potential inhibitors of HIV-1 protease

This research has focused on the development of novel coumann derivatives containing peptide-like side chains as potential HIV-1 protease inhibitors. The reaction of various salicylaldehyde derivatives with tert-butyl acrylate In the presence of 1,4- diazabicyclo[2.2.2]octane (DABCO) has afforded a...

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Bibliographic Details
Main Author: Rose, Nathan Rolf
Format: Others
Language:English
Published: Rhodes University 2007
Subjects:
Coumarins
Protease Inhibitors
Heterocyclic compounds > Derivatives
HIV infections > Treatment
Online Access:http://hdl.handle.net/10962/d1007220

Internet

http://hdl.handle.net/10962/d1007220

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