Acute simulated hypoxia and ischemia in cultured C2C12 myotubes : decreased phosphatidylinositol 3-kinase (PI3K)/Akt activity and its consequences for cell survival

Thesis (MSc (Physiological Sciences))--Stellenbosch University, 2008. === Cells are equipped with an array of adaptive mechanisms to contest the undesirable effects of ischemia and the associated hypoxia. Indeed, many studies have suggested that there is an increase in the PI3K/Akt pathway activat...

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Bibliographic Details
Main Author: Thomas, Mark Peter
Other Authors: Engelbrecht, Anna-Mart
Language:en
Published: Stellenbosch : Stellenbosch University 2008
Subjects:
Online Access:http://hdl.handle.net/10019.1/2610