Role of glycogen synthase kinase 3 (GSK-3) and its substrate proteins in the development of cardiomyopathy associated with obesity and insulin resistance

Thesis (MScMedSc)--University of Stellenbosch, 2011. === ENGLISH ABSTRACT: INTRODUCTION: Glycogen synthase kinase-3 (GSK-3) is a serine-threonine protein kinase that was first discovered as a regulator of glycogen synthase thus playing a role in glycogen synthesis (Embi et al. 1980). GSK-3 has also...

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Bibliographic Details
Main Author: Flepisi, Thabile Brian
Other Authors: Huisamen, B.
Format: Others
Language:en_ZA
Published: Stellenbosch : University of Stellenbosch 2011
Subjects:
Online Access:http://hdl.handle.net/10019.1/6795