Identification of mechanisms regulating the intra cellular concentration of rifampicin in Mycobacterium Tuberculosis

Thesis (PhD)--Stellenbosch University, 2013. === ENGLISH ABSTRACT: Rifampicin resistance in clinical isolates of Mycobacterium tuberculosis develops through selection of bacterial variants harbouring mutations in the rpoB gene. These mutations infer a fitness-cost in the absence of antibiotic pressu...

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Bibliographic Details
Main Author: De Vos, Margaretha
Other Authors: Victor, Thomas Calldo
Format: Others
Language:en_ZA
Published: Stellenbosch : Stellenbosch University 2013
Subjects:
Online Access:http://hdl.handle.net/10019.1/79794