Identification of mechanisms regulating the intra cellular concentration of rifampicin in Mycobacterium Tuberculosis
Thesis (PhD)--Stellenbosch University, 2013. === ENGLISH ABSTRACT: Rifampicin resistance in clinical isolates of Mycobacterium tuberculosis develops through selection of bacterial variants harbouring mutations in the rpoB gene. These mutations infer a fitness-cost in the absence of antibiotic pressu...
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Format: | Others |
Language: | en_ZA |
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Stellenbosch : Stellenbosch University
2013
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Online Access: | http://hdl.handle.net/10019.1/79794 |