Design of an optimised fed-batch process for insulin precursor production in Pichia pastoris
Includes bibliographical references (leaves 98-103). === The increasing prevalence of diabetes worldwide has greatly increased the demand for insulin, a key type of treatment for many diabetics. For this purpose, the methylotrophic yeast Pichia pastoris has emerged as an additional microbial host fo...
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Format: | Dissertation |
Language: | English |
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University of Cape Town
2014
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Online Access: | http://hdl.handle.net/11427/10120 |