Pharmacogenetics of Efavirenz response in Bantu-speaking South African HIV/AIDS patients
Includes abstract. === Includes bibliographical references (leaves 82-96). === Efavirenz (EFV) is used in first-line antiretroviral (ARV) therapy of HIV-infected patients, and is principally metabolised by CYP1A2, CYP2A6, CYP2B6, CYP3A4/5 and the drug transporter ABCB1. Genetic variability in the ab...
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| Format: | Dissertation |
| Language: | English |
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University of Cape Town
2015
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| Online Access: | http://hdl.handle.net/11427/11835 |