Synthesis and investigation of quinoline based ß-haematin formation inhibitors as potential antimalarials
Includes abstract. === Includes bibliograhical references. === The question of whether or not replacing the 7-chloro group in the 4-aminoquinoline moiety with an electron withdrawing and hydrophilic substituent results in retention of antiplasmodial activity in the 4-aminoquinoline class of compound...
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| Format: | Doctoral Thesis |
| Language: | English |
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University of Cape Town
2015
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| Online Access: | http://hdl.handle.net/11427/12176 |