The role of the cytolytic mediators, granulysin and perforin, in tuberculosis
Includes bibliographical references (leaves 150-175). === Includes abstract. === Protective immunity against mycobacterial infection requires an effective cytolytic response, in addition to an intact Type l (Th1) cytokine pathway. Natural killer (NK) cells and cytolytic T-cells (CTL) are essential c...
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Format: | Doctoral Thesis |
Language: | English |
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University of Cape Town
2015
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Online Access: | http://hdl.handle.net/11427/12403 |