Design and synthesis of potential inhibitors of enzymes involved in the biosynthesis and utilisation of mycothiol
Includes bibliographical references. === This thesis describes the synthesis of several naphthoquinone- and carbazole-1,4-quinone-derived conjugates of a mycothiol-like scaffold designed to act as redox cycling subversive substrates of the enzyme, Mtr, or potentially inhibit other mycothiol-dependen...
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| Format: | Doctoral Thesis |
| Language: | English |
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University of Cape Town
2015
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| Online Access: | http://hdl.handle.net/11427/12674 |