The role of N-linked glycosylation on the structure and function of somatic angiotensin-converting enzyme
Angiotensin converting enzyme (ACE) is a key regulator of blood pressure and comprised of two homologous domains (N- and C-domain), both of which are glycosylated. N-linked glycosylation is important for the processing, expression and stability of ACE, but it interferes with protein crystallization....
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Format: | Dissertation |
Language: | English |
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University of Cape Town
2015
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Online Access: | http://hdl.handle.net/11427/13971 |