The role of N-linked glycosylation on the structure and function of somatic angiotensin-converting enzyme

Angiotensin converting enzyme (ACE) is a key regulator of blood pressure and comprised of two homologous domains (N- and C-domain), both of which are glycosylated. N-linked glycosylation is important for the processing, expression and stability of ACE, but it interferes with protein crystallization....

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Bibliographic Details
Main Author: Nkoe, Karabelo M
Other Authors: Sturrock, Edward D
Format: Dissertation
Language:English
Published: University of Cape Town 2015
Subjects:
Online Access:http://hdl.handle.net/11427/13971