Molecular mechanisms involved in the anticancer activity of BISPMB in oesophageal cancer cells

BisPMB (E, Z)-1,8-(Bis-p-methoxyphenyl)-2,3,7-trithiaocta-4-ene 7-oxide) is a synthetic analogue of the garlic compound ajoene. It is 12 times more active at inhibiting the growth of oesophageal squamous cell carcinoma WHCO1 cells and displays selectivity for cancer cells over normal cells. BisPMB i...

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Bibliographic Details
Main Author: Siyo, Vuyolwethu Penelope
Other Authors: Parker, Iqbal
Format: Doctoral Thesis
Language:English
Published: University of Cape Town 2016
Subjects:
Online Access:http://hdl.handle.net/11427/20422