Investigating the genetic basis of cisplatin-induced ototoxicity in adult South African patients

Cisplatin, a potent chemotherapeutic agent, is widely used in the treatment of numerous soft-tissue cancers. Although high cure rates can be achieved when cisplatin is incorporated in chemotherapy regimens, the therapeutic utility of the drug may be limited by the development of dose-limiting advers...

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Bibliographic Details
Main Author: Spracklen, Timothy Francis
Other Authors: Ramesar, Rajkumar
Format: Dissertation
Language:English
Published: University of Cape Town 2016
Subjects:
Online Access:http://hdl.handle.net/11427/20540