Computer-aided drug design and the biological evaluation of anti-cancer drugs

Computer-aided drug design has become a promising alternative to high-throughput screening by identifying potential hits in silico for in vitro evaluation. In this study a combination of ligand-based and structure-based virtual screening was performed to identify in silico hits. This was based on fi...

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Bibliographic Details
Main Author: Moorad, Razia
Other Authors: Zerbini, Luiz F
Format: Doctoral Thesis
Language:English
Published: University of Cape Town 2016
Subjects:
Online Access:http://hdl.handle.net/11427/20715