Characterising the anticancer effects of a small molecule with potential to inhibit nuclear import via karyopherin beta1
The Karyopherin superfamily is a group of soluble transport proteins which are involved in nuclear-cytoplasmic trafficking. Studies have shown the involvement of Karyopherin proteins in nuclear pore assembly, nuclear membrane assembly and DNA replication. Since all these cell regulatory functions ar...
| Main Author: | |
|---|---|
| Other Authors: | |
| Format: | Dissertation |
| Language: | English |
| Published: |
University of Cape Town
2018
|
| Subjects: | |
| Online Access: | http://hdl.handle.net/11427/27887 |