Characterisation of HIV-1 subtype C envelope functional determinants of dual infected individuals
Identification of HIV-1 Envelope (Env) fitness determinants could provide functionally constrained, accessible regions that could be included in subunit vaccines to induce broadly neutralising antibodies (bnAb). We hypothesised that Env fitness determinants are common to circulating variants but tha...
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Format: | Doctoral Thesis |
Language: | English |
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University of Cape Town
2019
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Online Access: | http://hdl.handle.net/11427/29417 |