The role of genetic variation in VKORC1 and GGCX on warfarin response in a South African population

Background: Warfarin is the most commonly used drug in the management of thromboembolic disease. However, there is a huge variability in the management of warfarin affecting the international normalized ratio (INR). Many genetic-association studies have reported on European and Asian populations whi...

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Bibliographic Details
Main Author: Cindi, Zinhle
Other Authors: Dandara, Collet
Format: Dissertation
Language:English
Published: University of Cape Town 2019
Subjects:
Online Access:http://hdl.handle.net/11427/29461