Supramolecular derivatisation of bioactive molecules via co-crystallization and cyclodextrin inclusion complexation
The objective of this study was to modify the physicochemical properties of two common drugs via supramolecular derivatization. Sulfasalazine is a powerful anti-inflammatory drug and fluconazole has a strong antibacterial and antifungal activity. The common feature is their very low solubility in wa...
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Format: | Dissertation |
Language: | English |
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University of Cape Town
2019
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Online Access: | http://hdl.handle.net/11427/29711 |