Supramolecular derivatisation of bioactive molecules via co-crystallization and cyclodextrin inclusion complexation

The objective of this study was to modify the physicochemical properties of two common drugs via supramolecular derivatization. Sulfasalazine is a powerful anti-inflammatory drug and fluconazole has a strong antibacterial and antifungal activity. The common feature is their very low solubility in wa...

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Bibliographic Details
Main Author: Sala, Andrea
Other Authors: Caira, Mino R
Format: Dissertation
Language:English
Published: University of Cape Town 2019
Subjects:
Online Access:http://hdl.handle.net/11427/29711