Antimalarial imidazopyridazines and aminopyrazines: synthesis, physicochemical optimization and structure-activity relationships

According to the World Health Organization (WHO) world malaria report released in 2017, about 445,000 malaria deaths were recorded in 2016, a similar mortality as that recorded in the preceding year (446,000 deaths in 2015). Once effective and cheap drugs such as chloroquine and sulfadoxine-pyrimeth...

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Bibliographic Details
Main Author: Cheuka, Peter Mubanga
Other Authors: Chibale, Kelly
Format: Doctoral Thesis
Language:English
Published: Faculty of Science 2019
Online Access:http://hdl.handle.net/11427/29985