Ligand-induced selective signalling at the gonadotrophin releasing hormone receptor

Includes abstract. === Includes bibliographical references (p. 179-202). === The pituitary gonadotrophin releasing hormone (GnRH) receptor regulates reproduction by activation of Gq/11 proteins. In contrast, GnRH receptors at extrapituitary sites induce anti-proliferative effects that do not correla...

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Bibliographic Details
Main Author: Coetsee, Marla Catherine
Other Authors: Flanagan, Colleen
Format: Doctoral Thesis
Language:English
Published: University of Cape Town 2014
Subjects:
Online Access:http://hdl.handle.net/11427/3123