The temporal requirement of IL-4Rα signalling in allergic asthma and the role of IL-4Rα-responsive Regulatory T cells in restraining allergic airway inflammation
Allergic asthma is a chronic inflammatory airway disease driven predominantly by a TH2 immune response to environmental allergens. The asthma pathology is predominantly elicited by IL-4 and IL-13 signalling via IL-4Rα-signalling which is essential for driving TH2-type immunity to allergens. Interest...
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| Format: | Doctoral Thesis |
| Language: | English |
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Faculty of Health Sciences
2020
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| Online Access: | https://hdl.handle.net/11427/31728 |