The fluroxene mediated degradation of cytochromes P-450

The degradation of cytochromes P-450 by fluroxene (2,2,2-trifluoroethyl vinyl ether) has been investigated. Fluroxene is shown to specifically degrade cytochromes P-450 in vivo and in vitro without affecting the levels of the other microsomal enzymes, cytochrome ~S a.nd NADPH-cytochrome~ reductase....

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Bibliographic Details
Main Author: Bradshaw, Jennifer Jean
Other Authors: Ivanetich, Kathryn M.
Format: Dissertation
Language:English
Published: Faculty of Health Sciences 2020
Subjects:
Online Access:https://hdl.handle.net/11427/31857